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Published 17:23 11 Feb 2016 GMT
The results, published in Scientific American, were based on a series of memory tasks for mice involving object recognition and location.
The mice were split into two groups – healthy weight and overweight – and were tracked on their ability to recognise, retain information, and make decisions based on memory.
Researchers found that compared to their healthy weight counterparts, overweight mice performed poorly on a spatial memory task - which relies on the brain's hippocampus.
The hippocampus is a small organ and forms an important part of the limbic system, the region that regulates emotions. The hippocampus is associated mainly with memory - particularly long-term memory. The organ also plays an important role in spatial navigation.
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