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Published 22:50 26 Feb 2017 GMT
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However, the other finding presented from the research is that people with this gene, an estimated 1 in 1,700, were also eighty percent more likely to have a heart attack.
Speaking to BBC News, Professor Adam Butterworth from Cambridge University said:
"This is significant because we had always believed that good cholesterol is associated with a lower risk of heart disease. "This is one of the first studies to show that some people that have high levels of 'good' cholesterol actually have a higher risk of heart disease so it challenges our conventional wisdom about whether 'good' cholesterol is protecting people from heart disease or not."
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