The Gunners travel to the Champions.
It was a close fought race for the title last season between Mikel Arteta’s Arsenal and Pep Guardiola’s City.
In the end, just like the season before, it was City who held their nerve to be crowned Champions.
Though this season is still in its infancy, this game feels like it could be crucial come the end of the season.
City have yet to drop points as they sit second behind Liverpool on 12 points while the Gunners are two points behind having drawn against Brighton in game week three.
Arsenal will be without Martin Odegaard again after he was side-lined with an ankle injury he sustained playing for Norway.
Declan Rice returns from suspension.
Meanwhile, Kevin de Bruyne was forced off in City’s Champions League clash with Inter Milan midweek with a suspected hamstring injury and it is unclear whether that will rule him out completely against Arsenal with Guardiola earlier hinting that the Belgium was ‘feeling better’.