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Published 21:16 24 Oct 2016 BST
Updated 21:23 24 Oct 2016 BST
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Promoter Eddie Hearn said: "We've been in deep negotiations for a few weeks now waiting on the decision from the WBA.
"I was made aware that Wladimir picked up a minor injury late last week but regardless of that, with just over six weeks to go til December 10, it's unrealistic to put together a fight of this magnitude and give it the full build up it deserves.
"There will be an official announcement on Joshua v Klitschko coming very soon but for now we are seeking a new foe for December 10 and building a huge card for Manchester."
There have been a few names bandied about in recent weeks including Lucas Browne - who holds a version of the WBA world heavyweight title - and unbeaten New Zealander Joseph Parker, who is a mandatory challenger for Joshua's belt.
Fellow British heavyweight David Price has also thrown his hat into the ring for a big money bout with Joshua, who has 17 KO wins on his record.
Klitschko though will still be desperate to fight AJ, who is the biggest draw in heavyweight boxing right now, but it looks like a potential match-up would have to wait until next year.
Fans were obviously gutted that this tantalising bout has now been put on ice...
https://twitter.com/jackburnessharp/status/790646870699827200
https://twitter.com/MohamedElmi1994/status/790646362408939520
https://twitter.com/StephenD35/status/790646267911217153
https://twitter.com/leewilliams_1/status/790646166438436864
https://twitter.com/jonnyescott/status/790645645803749376
https://twitter.com/Jurassic_Parky/status/790645101374603264
https://twitter.com/MichaelBensonn/status/790644983598608384
https://twitter.com/owiddo96/status/790644749669498880
https://twitter.com/shaunmulhern95/status/790644616521453568
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