These are the most wanted fugitives in Britain

The list includes charges of murder, organised criminal activity and large scale money laundering

The National Crime Agency's most wanted list may not be as glamorous as the FBI's, once famously graced by Osama Bin Laden's presence, but it is populated by serious crimes. There are fugitives accused of running international cocaine distribution network, cold-blooded murder and laundering more than £1 billion. There is a reward of £50,000 for information leading to the arrest and prosecution of some of the most wanted. If you know the whereabouts of a wanted fugitive please contact the independent charity Crimestoppers anonymously, via their online form or by calling 0800 555 111. Crimestoppers guarantee your anonymity; no-one will ever know who you are, you will not have to give a statement to the police and you will never have to go to court. It's important to not approach any person featured in this list. In an emergency, call 999.

Costas Simpson

On August 25 2012 Sampson was convicted of raping a girl he met at a nightclub in London in February 2010. The girl was taken unwell after accepting a drink from a stranger, and Sampson and a friend offered to take her home. Sampson told one of the girl’s friends that he was a medical expert. He later raped the girl at her flat while she was incapacitated. Sampson was also convicted of stealing her mobile phone, plus her flatmate’s laptop and games console.

Simon McGuffie, 41

Wanted by the North West Regional Organised Crime Unit (Titan) on suspicion of being a member of a Merseyside-based organised crime group involved in the large-scale supply of cocaine, heroin and cannabis across the North West. He has a scarred right arm and distinctive 2” scar to the right cheek.

Mark Quinn, 52

Wanted by Police Scotland on suspicion of supplying amphetamine. Between August 2013 and April 2014 Quinn was allegedly involved in an organised crime group concerned in the production, transportation and distribution of amphetamine with a street value of over £11m. He is described as 5ft 9ins tall, large build and has short brown hair.

Dominic McInally, 25

Wanted by Merseyside Police on suspicion of conspiracy to supply cocaine. McInally is the alleged leader of a drug trafficking gang that expected to bank £1.25m every month. Members of the gang travelled to the border of France and Belgium to pick up six kilos of cocaine. The package, hidden in a secret compartment inside a Seat Leon car, was intercepted by police officers when they swooped on the gang near Crosby in January 2014. McInally evaded capture. Five members of the gang have received sentences totalling 48 years. He is described as 178cm tall and has blond hair.

Mark Aklom, 43

Wanted by Avon & Somerset Police on suspicion of fraud by false representation. Acklom allegedly made a number of false representations after starting a romantic relationship with a woman from Bath in January 2012. She said Acklom first claimed to work in the banking world in Switzerland and was very wealthy, and then later went on to say he worked for an intelligence agency. During their relationship she said they discussed marriage. After saying he had cash flow problems that were hindering renovation work at one of the properties he wanted them to live in, the woman gave him numerous loans totalling £850,000. It later transpired that Acklom did not own the property. He disappeared and she never received any of her money back. He is described as 5ft 10ins tall, medium build, dark brown hair and green eyes.

Sarah Panitzke, 42

Wanted by HMRC for conspiracy to acquire criminal property. Panitzke was a senior member of a crime group involved in a VAT fraud. She controlled the company accounts of many companies remotely via different IP addresses. Panitzke travelled extensively to further the fraud to places including Dubai, Spain and Andorra. She was responsible for laundering approximately £1billion pounds. Panitzke absconded in May 2013 prior to the end of the trial and was convicted in her absence. She was sentenced to eight years on August 22 2013. Eighteen members of the crime group received sentences totalling 135 years. She is described as 170cm tall, slim build with mousey straight hair, blue eyes and has a Yorkshire accent.

David Ungi

In July 2015, Ungi and two associates were in a vehicle on Banks Road in Garston, Liverpool, which police believe rammed a motorcycle carrying two males. A single shot from a 12-gauge shotgun was fired inflicting a fatal injury to one of the men and injuring the other. The murder victim was Garston teenager Vinny Waddington. Ungi is also alleged to be involved in the unlawful distribution of heroin in the Liverpool area.

Jonathon Kelly, 36

Wanted by Police Scotland on recall to prison to serve remaining sentence of 9 years 10 months for a number of serious assaults. Kelly, who is extremely violent and poses a high risk to both police and members of the public, was convicted at various courts of a number of offences between 2002 and 2010. He received sentences in excess of 16 years, and in September 2013 he was released on licence but failed to adhere to conditions set. The offences he was convicted of included an assault to severe injury and danger of life, robbery, assault to severe injury and permanent disfigurement, breach of the peace and having a sharply pointed implement in prison. In one of the most serious assaults Kelly stabbed and paralysed his victim using a machete. He is described as 180cm tall, heavy build, blue/grey eyes, short brown hair, Scottish accent, and occasionally has a beard. Also has scars to the left and right side of the face, on his arms and his right hand.

Jamie Acourt, 40

Wanted by the Metropolitan Police on suspicion of conspiracy to supply cannabis resin between 1 January 2014 and 1 February 2016. Acourt is believed to be a principal member of an organised crime group involved in the large-scale supply of cannabis. He is described as 173cm tall, athletic build, pale complexion, dark brown hair, brown eyes, and sometimes wears glasses.

Shane O'Brien

In October 2015 O’Brien was in the RE Bar in Field End Road, Eastcote, Hillingdon, with several friends. It is alleged that O’Brien approached 21-year-old Josh Hanson from Kingsbury, who was with his girlfriend at the bar, removed an item from his coat pocket and plunged it into his neck. He was pronounced dead at the scene.

O'Brien is believed to be in Europe and has changed his appearance since Josh's murder, with long hair, a full beard and a tattoo of an owl holding a skull. He has been using the Italian aliases Enzo Melloncelli and Enzo Machado.

A reward of up to £50,000 is available for information leading to O’Brien’s arrest and prosecution.