Manchester United have been handed a tie with St-Etienne as they bid for glory in the Europa League.
Jose Mourinho's side will battle the Ligue Un side for a place in the last 16, as the Portuguese boss tries to reclaim the trophy he won with Porto back in 2003.
The Premier League's other representatives Tottenham Hotspur will take on Belgium side Gent.
Ties will be played on February 16, with the return legs seven days later.
The full draw:
Athletic Bilbao vs Apoel FC
Legia Warszaw vs Ajax
Anderlecht vs Zenit
FC Astra Giurgiu vs KRC Genk
Manchester United vs St-Etienne
Villarreal vs AS Roma
Ludogorets vs FC Copenhagen
Celta Vigo vs Shakhtar Donetsk
Olympiacos vs Osmanlispor
KAA Gent vs Tottenham
FC Rostov vs Sparta Prague
Krasnodar vs Fenerbahce
Borussia Monchengladbach vs Fiorentina
AZ Alkmaar vs Lyon
Hapoel Be’er Sheva vs Besiktas
PAOK FC vs Schalke
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