
News
Share
Published 18:04 4 May 2025 BST
Updated 18:06 4 May 2025 BST

Tim Friede, an ex-truck mechanic from California, has single-handedly altered the course of antivenom production with his unique blood.
Since 2007, he's been injecting himself with snake venom and allowing the reptiles to sink their fangs into him as a way of building immunity when handling them - clocking up over 700 injections and 200 bites in the process - and helping those in need of life-saving treatment following animal attacks.
"I didn't want to die. I didn't want to lose a finger. I didn't want to miss work," Friede told BBC.
"It just became a lifestyle and I just kept pushing and pushing and pushing as hard as I could push - for the people who are 8,000 miles away from me who die from snakebite."
He eventually came to the attention of Centivax chief executive Dr. Jacob Glanville, whose team was searching for 'broadly neutralising antibodies'.
"Immediately I was like, 'If anybody in the world has developed these broadly neutralising antibodies, it's going to be him' and so I reached out," said Glanville.
"The first call I was like, 'This might be awkward, but I'd love to get my hands on some of your blood.'"
Friede was happy to assist in the project, which focused on the elapid family of venomous snakes (cobras, taipans and mambas) that use neurotoxins to paralyse their victims. This allowed Glanville and his team to scour his blood for protective components.
Their research found two broadly neutralising antibodies that could target two classes of neurotoxin; adding in a third drug to complete an experimental antivenom brew to be used on mice.
These mice survived fatal doses from 13 of the 19 specially selected species of deadly snake, while they had partial protection against the other six.
Glanville called this "unparalleled" protection and the team is now trying to refine these antibodies to see if a fourth element can result in total protection against elapid venom.
Columbia University's Professor Peter Kwong believes that in the next "10 or 15 years" we should have effective antivenom against the vipers' haemotoxins too, which target the blood, but the ultimate aim is to concoct one single antivenom against both classes of snake.
"Tim's antibodies are really quite extraordinary - he taught his immune system to get this very, very broad recognition," noted Kwong.
Friede went on to say: "I'm doing something good for humanity and that was very important to me. I'm proud of it. It's pretty cool."
Rejoining EU could boost UK economy by £150bn – Goldman Sachs
Analysts from the bank reckon a ‘Breturn’ would boost the UK economy by 2-5% by the start of the next decade. Goldman Sachs has said rejoining the European Union could boost the UK economy by as much as £150 billion. In a note to clients, the Wall Street bank voiced its support for Andy Burnham’s […]
News
3h
Travel chaos across Italian airports after air traffic control failure
Air traffic management capacity has been slashed in half Travel chaos has struck Italy’s major airports after an air traffic control failure left capacity halved on Friday. Hundreds of flights across Italy have been delayed and over 100 cancelled due to “anomalies” with air traffic control (ATC) services. The Italian air navigation service provider, ENAV, […]
News
8h
News
Abu Dhabi Royal was found passed out on street in London after ‘cocaine binge’
News